Programmed Cell Death in the Developing Nervous System

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Programmed Cell Death in the Developing Nervous System

Virtually all cell populations in the vertebrate nervous system undergo massive "naturally-occurring" or "programmed" cell death (PCD) early in development. Initially neurons and glia are overproduced followed by the demise of approximately one-half of the original cell population. In this review we highlight current hypotheses regarding how large-scale PCD contributes to the construction of th...

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Programmed cell death in the nervous system--a programmed cell fate?

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ژورنال

عنوان ژورنال: Neuron

سال: 1996

ISSN: 0896-6273

DOI: 10.1016/s0896-6273(00)80191-9